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Medical Director_Neurodevelopmental Disorders

1201 F. Hoffmann-La Roche AG
place
Basel, CH-BS

5T

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Medical Director_Neurodevelopmental Disorders

At Roche, we believe it is urgent to deliver medical solutions now - even as we develop innovations for the future. We are passionate about improving the lives of patients with brain diseases, and strive for ambitious ideas, innovative approaches and urgent action. Our belief is that our success as a company will come from developing therapies for patients in need, which is why we come to work every single day. We commit ourselves to scientific rigor, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow.

Within Roche's Pharma Research and Early Development (pRED), Neuroscience & Rare Diseases represents a major focus area where we are committed to realizing our long-term vision of changing lives of patients with severe brain disorders. Our preclinical research and early clinical development activities center around large and rare indications. With unparalleled strengths across diverse disciplines, Roche is uniquely positioned to lead in transforming science to medicines for patients with disorders of the nervous system.

To achieve our goals, Roche pRED Neuroscience & Rare Diseases is seeking a Medical Director within our Early Development department, focusing on neurodevelopmental disorders.

The Position:

In this role, you will lead early stage clinical projects through proof of mechanism and proof of concept, to transform molecules into new medicines in an area with huge unmet medical need.

Your main responsibilities are:

  • Lead clinical expert teams and represent them at the project team level
  • Lead the clinical development plan from Phase 0 (clinical candidate selection) through completion of Phase 2 (proof-of-concept)
  • Develop, review and approve clinical protocols, IBs, ICFs, eCRFs, medical monitoring plans in collaboration with clinical scientists in early development and clinical pharmacology
  • Provide medical monitoring support for ongoing clinical trials
  • Manage, coach and support Clinical Scientists and/or Clinical Research Fellows in a line or functional manager status
  • Closely interface with safety, clinical pharmacology, clinical operations, biostatistics, regulatory, research and biomarker groups and other members of clinical project teams
  • Lead health authority interactions in collaboration with global regulatory leaders
  • Lead Scientific Advisory Board activities with external academic and research community in collaboration with research project leaders and with biomarker leaders
  • Provide clinical input to programs in early research, from target assessment to clinical lead selection
  • Lead scientific communications and disseminate the results of clinical trials in form of oral presentation, posters and/or publications
Who you are:

You are MD or MD/PhD with a specialty in child neurology (or similar) with a focus on neurodevelopmental disorders, including rare chromosomal and monogenic diseases of neurodevelopment.

Board certification in child neurology or related specialty, and fellowship training or research experience in relevant areas is preferred. Clinical care and clinical research experience in neurodevelopmental disorders, especially rare genetic diseases of neurodevelopment is required for the role.

At least 5 years of experience in longitudinal clinical research (observational and/or interventional) are required. A strong track record of scientific excellence in the field is essential, evidenced by a high level of scholarship in academia and/or substantial achievement in designing and implementing clinical trials in academia or in industry. Experience in clinical drug development within industry is a strong asset, ideally early stages of clinical development. As a leader, you will work within a matrix environment where influencing and inspiring others in striving for excellence is expected.

Are you ready to apply? Roche embraces diversity and equal opportunity in a serious way. We are committed to building teams that represent a range of backgrounds, perspectives, and skills.

If you still have questions then please check our FAQs and videos on careers.roche.ch/faq.